KT-413 |CAS 2655656-99-6|DC Chemicals

Cas No.:	2655656-99-6
Chemical Name:	IRAK degrader-1
Synonyms:	2655656-99-6;compound A [WO2022027058A1];SCHEMBL23696494;CS-0694448;N-[2-[4-[[6-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethyl]-2-azaspiro[3.3]heptan-2-yl]methyl]cyclohexyl]-5-(2-hydroxypropan-2-yl)-1,3-benzothiazol-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide;GTPL11904;SCHEMBL23696217;HY-153368;IRAK degrader-1;SCHEMBL23539538;N-[2-[trans-4-[[6-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-2-azaspiro[3.3]hept-2-yl]methyl]cyclohexyl]-5-(1-hydroxy-1-methylethyl)-6-benzothiazolyl]-6-(trifluoromethyl)-2-pyridinecarboxamide
SMILES:	S1C2C=C(C(C(C)(C)O)=CC=2N=C1C1CCC(CC1)CN1CC2(C1)CC(CCNC1=CC=CC3C(N(C4C(NC(CC4)=O)=O)C(C1=3)=O)=O)C2)NC(C1C=CC=C(C(F)(F)F)N=1)=O
Formula:	C₄₅H₄₈F₃N₇O₆S
M.Wt:	871.966139793396
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC68008	Tris-GalNAc-β-Ala-PEG3-FITC	The trivalent β-GalNAc ligand is specific for Asialo Glycoprotein Receptors (ASGPR) on hepatocyte cells. β-Ala-PEG3 acts as linker/spacer between triantennary GalNAc and Fluorescein isothiocyanate (FITC).
DC68007	Tris-GalNAc-β-Ala-PEG3-MAL	A thiol-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68006	Tri-GalNAc-PEG2000-DSPE	Tris-GalNAc-GABA-NH2 linked via PEG2k to phospholipid (DSPE or 1,2-distearoyl-sn-glycero-3-phosphoethanolamine) where GABA = gamma-Aminobutyric acid, or γ-aminobutyric acid.
DC68005	Tris-GalNAc-PEG5-sulfo-NHS Ester	An amine-reactive asialo glycoprotein receptor (ASGPR) ligand.
DC68004	Tris-GalNAc-β-Ala-PEG3-DBCO	Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry.
DC68003	Tris-GalNAc-β-Ala-PEG4-DBCO	Triantennary GalNAc ligand is known to bind Asialo Glycoprotein Receptor (ASGPR). The ligand is functionalized with dibenzocyclooctyne for click chemistry
DC68002	Tris-β-GalNAc-β-Ala-PEG3-N3	(β-D-GalNAc-sp)3-NHC(O)-(CH2)2-NHC(O)-PEG3-(CH2)2-N3 Tris-β-D-GalNAc ligands bind with asialoglycoprotein receptors (ASGPR) that are highly expressed on hepatocytes resulting in rapid endocytosis of the ligand along with conjugated payloads
DC68001	Tris-β-GalNAc-PEG3-Azide	Trivalent β-GalNAc Ligand with discrete, monodisperse, azido-functionalized PEG3 linker/spacer
DC68000	Tris-GalNAc-β-Ala-PEG3-NH2
DC67999	Tris-GalNAc-Ahx-NH2